Intestinal obstruction due to metastasis of renal cell carcinoma to the duodenum and the jejunum
Keywords:
renal neoplasms, metastasis of the neoplasm, duodenal neoplasms, jejunal neoplasms, intestinal obstruction.Abstract
Renal cell carcinoma currently represents 2%-3% of all cancers. Characterized as it is by its metastatic potential, it does not often affect the duodenum and the jejunum. A case is presented of a female 63-year-old patient with a history of left renal cell carcinoma treated by radical nephrectomy. Five years after the diagnosis, the patient reports a progressive sensation of fullness and satiety which has worsened with the passing of time until she attends the emergency service with a state suggestive of intestinal obstruction. Abdominal tomography reveals the presence of obstruction secondary to edema of the duodenal and jejunal submucosa. Duodenal biopsy is indicated, which confirms metastatic infiltration by the aforementioned renal tumor. Although metastatic damage to the small intestine by renal cell carcinoma is infrequent, it is a diagnosis to be considered in patients with symptoms of intestinal obstruction and a tumor history.
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2- Feng X, Zhang L, Tu W, Cang S. Frequency, incidence and survival outcomes of clear cell renal cell carcinoma in the United States from 1973 to 2014: A SEER-based analysis: Medicine (Baltimore). 2019;98(31):e16684. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708618/
3- Shuch B, Vourganti S, Ricketts CJ, Middleton L, Peterson J, Merino MJ, et al. Defining early-onset kidney cancer: implications for germline and somatic mutation testing and clinical management. J Clin Oncol. 2014 [acceso 18/02/2021];32(5):431-7. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912328/
4- Bianchi M, Sun M, Jeldres C, Shariat SF, Trinh Q-D, Briganti A, et al. Distribution of metastatic sites in renal cell carcinoma: a population-based analysis. Ann Oncol. 2012 [acceso 18/02/2021];23(4):973-80. Disponible en: https://annalsofoncology.org/article/S09323-7534(19)34655-1/fulltext
5- Zhang S, Zheng C, Chen Y, Xu Q, Ma J, Yuan W, et al. Clinicopathologic features, surgical treatments, and outcomes of small bowel tumors: A retrospective study in China. Int J Surg. 2017 [acceso 27/12/2020];43:145-54. Disponible en: https://www.clinicalkey.es/#!/content/1-s2.0-S1743919117304612
6- Kadakia SC, Parker A, Canales L. Metastatic tumors to the upper gastrointestinal tract: endoscopic experience. Am J Gastroenterol. 1992 [acceso 27/12/2020];87(10):1418-23. Disponible en: https://pubmed.ncbi.nlm.nih.gov/1415098/
7- Bannura G, Barrera A, Melo C, Illanes F. Tumores primarios del yeyuno-íleon: correlación clínico-patológica. Rev Chil Cir. 2012;64(3):264-73. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0718-40262012000300008
8- Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7-33. Disponible en: https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21654
9- Park HJ, Kim HJ, Park SH, Lee JS, Kim AY, Ha HK. Gastrointestinal involvement of recurrent renal cell carcinoma: CT findings and clinicopathologic features. Korean J Radiol. 2017 [acceso 27/12/2020];18(3):452. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390614/
10- Sadler GJ, Anderson MR, Moss MS, Wilson PG. Metastases from renal cell carcinoma presenting as gastrointestinal bleeding: two case reports and a review of the literature. BMC gastroenterol. 2007 [acceso 27/12/2020];7:4. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800859/
11- Omranipour R, Mahmoud Zadeh H, Ensani F, Yadegari S, Miri SR. Duodenal metastases from renal cell carcinoma presented with Melena: Review and case report. Iran J Pathol. 2017 Summer [acceso 27/12/2020];12(3):272–6. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835376/
12- Piskorz Ł, Mitura K, Olejniczak W, Misiak P, Jablonski S. Atypical locations of renal cell carcinoma metastases to the pancreas and duodenum. Res Rep Urol. 2021 [acceso 20/03/2021];13:17–24. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814245/
13- Kojima Y, Matsumoto F, Mikami Y, Namekata K, Takei M. Metastatic small bowel tumor from descending colon cancer with extensive hematogenous or lymphogenous spread: Survey of the Japanese literature. Case Rep Gastroenterol. 2010 [acceso 20/03/2021];4(3):340–5. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974996/
14- Warschauer EG, Maggi F, Maggi P. Small bowel obstruction caused by intussusception secondary to metastatic melanoma. Ann Ital Chir. 2020 [acceso 20/03/2021];9:S2239253X20031795. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32170051/
15- Bellio G, Cipolat Mis T, Kaso G, Dattola R, Casagranda B, Bortul M. Small bowel intussusception from renal cell carcinoma metastasis: a case report and review of the literature. J Med Case Rep. 2016 [acceso 20/03/2021];10(1):222. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980778/
16- Adamo R, Greaney PJ Jr., Witkiewicz A, Kennedy EP, Yeo CJ. Renal cell carcinoma metastatic to the duodenum: treatment by classic pancreaticoduodenectomy and review of the literature. J Gastrointest Surg. 2008 [acceso 20/03/2021];12(8):1465-8. Disponible en: https://pubmed.ncbi.nlm.nih.gov/18066632/
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Published
2021-09-06
How to Cite
1.
Bobadilla Romero ER, Marín Martínez FM, Artés Artés M, García Porcel V. Intestinal obstruction due to metastasis of renal cell carcinoma to the duodenum and the jejunum. Rev. Cubana Urol. [Internet]. 2021 Sep. 6 [cited 2024 Dec. 22];10(3). Available from: https://revurologia.sld.cu/index.php/rcu/article/view/718
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